Thymosin α1/ Thymosin α1 / AcetateThymosin Alpha 1 CAS 162304-98-7 For Treat chronic hepatitis B and boosting the immune system

Thymosin α1/ Thymosin α1 / AcetateThymosin Alpha 1 CAS 162304-98-7 For Treat chronic hepatitis B and boosting the immune system

Product Name: Thymosin α1
Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Glu-Val-Glu-Glu-Ala-Glu-Ala-Glu-Asn-OH
Synonyms: THYMOSIN ALPHA 1;THYMOSIN ALPHA1 BOVINE;THYMOSIN APHA 1;ZADAXIN;Thymosin α1 Acetate;Thymosin αAcetate salt;Thymalfasin Acetate salt;Thymosin α 1 Acetate(Thymalfasin)
CAS: 62304-98-7
MF: C129H215N33O55
MW: 3108.32
EINECS: 1592732-453-0
Product Categories: Amino Acid Derivatives;Peptide;Various Peptides
Mol File: 62304-98-7.mol

Thymosin-α1 (T-α1), a synthetic 28-amino acid peptide with multiple biological activities primarily directed towards immune response enhancement, this drug is used for the treatment of HBV and hepatitis C virus (HCV) infections, and being developed for the treatment of non-small cell lung cancer (NSCLC), hepatocellular carcinoma, AIDS and malignant melanoma. T-α1 is able to potentiate the action of cytokines and also reduce the hematological toxicity of cytotoxic drug therapy, such as cyclophosphamide, 5-fluorouracil, dacarbazine.

Thymosin α1/ Thymosin α1 / AcetateThymosin Alpha 1 CAS 162304-98-7 Chemical Properties
Boiling point 2899.7±65.0 °C(Predicted)
density 1.360±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility It is recommended to reconstitute the lyophilized Thymosin a1 in sterile 18MΩ-cm H2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.
color Sterile Filtered White lyophilized (freeze-dried) powder.
Stability: Lyophilized Thymosin a1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Thymalfasin should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Function and Application of Thymosin α1/ Thymosin α1 / AcetateThymosin Alpha 1 CAS 162304-98-7
Thymosin α1 is a chemically synthesized thymosin α1 that is identical to human thymosin α1. Thymosin α1 is an acetylated polypeptide. Thymosin α1 is currently approved for the treatment of hepatitis B and C in 35 developing countries. Also, thymosin α1 is used to enhance the immune response in the treatment of other diseases.

Thymosin alpha 1 Benefits
Thymalfasin (thymosin-alpha 1) is an immunomodulating agent able to enhance the Thl immune response. In vitro: conjugation of thymalfasin (Tα1) with iRGD preserves the immunomodulatory activity of the drug by increasing the proliferation of mouse spleen lymphocytes. Further, compared with Tα1 treatment, Tα1-iRGD treatment of MCF-7 cells considerably increases the number of cells undergoing apoptosis, resulting in a dose-dependent inhibition of cancer cell growth.

In vivo: Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects.

Thymosin alpha 1 Dosage
This depends on your body weight. All of the research carried out so far has used rodent studies, the rats and mice are usually injected with an effective dosage thought to be around 10 μg (mcg) per KG, in humans this is thought to be around the equivalent loading of 1.6 μg per KG in humans, so if you are:

60 KG (132 lb.) then your ideal daily BPC-157 oral dose would be 96 μg (mcg)
70 KG (154 lb.) => 112 μg
80 KG (176 lb.) => 128 μg
90 KG (198 lb.) => 144 μg