Puya Supply Eptifibatide CAS 188627-80-7 Inhibits platelet aggregation and thrombosis

Puya Supply Eptifibatide CAS 188627-80-7 Inhibits platelet aggregation and thrombosis

Product Name: Eptifibatide
Synonyms: Eptifibatide acetate salt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2, >99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDE BRIDGE, MPA1-CYS6);Intrifiban
CAS: 188627-80-7
MF: C35H49N11O9S2
MW: 831.96
EINECS: 641-366-7
Product Categories: Intermediates & Fine Chemicals;Peptides;Pharmaceuticals
Mol File: 188627-80-7.mol

Eptifibatide is a kind of synthetic cyclic hexapeptide consisting of 6 amino acids and 1 mercaptopropionyl residue. It is capable of binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibiting the platelet aggregation, thus blocking the binding of the fibrinogen, von Willebrand factor and other adhesive ligands. It is indicated for the treatment of acute coronary syndrome (ACS) and Percutaneous coronary intervention (PCI). It is able to reduce the risk of acute cardiac ischemic events in patients with unstable angina or non-ST segment-elevation myocardial infection. It is often used in combination with aspirin or clopidogrel and heparin. It can be manufactured through solution-phase peptide synthesis, and can be purified by preparative reverse-phase liquid chromatography and lyophilization.

Eptifibatide CAS 188627-80-7 Chemical Properties
density 1.60±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
pka 4.01±0.10(Predicted)
CAS DataBase Reference 188627-80-7

Function and Application of Eptifibatide CAS 188627-80-7
A Arginin-glycin-aspartat-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.