Pentapeptide-18/ Leuphasyl CAS 64963-01-5 Anti-Wrinkle and Smooth Skin

Pentapeptide-18/ Leuphasyl CAS 64963-01-5 Anti-Wrinkle and Smooth Skin

Product Name: TYR-D-ALA-GLY-PHE-LEU/ Pentapeptide-18/ Leuphasyl
Synonyms: H-TYR-D-ALA-GLY-PHE-LEU-OH;(D-ALA2)-LEU-ENKEPHALIN;D-ALA2-LEU5-ENKEPHALIN;[D-ALA2]-LEUCINE ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine;(D-alanine2)leucine enkephalin;L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH
CAS: 64963-01-5
MF: C29H39N5O7
MW: 569.65
EINECS: 265-291-0
Product Categories:
Mol File: 64963-01-5.mol

Leuphasyl is an amid peptide, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors. It targets in vitro the wrinkle-formation mechanism of expression wrinkles in a new way, offering an alternative to peptides like Acetyl Hexapeptide-3. It is a potent, long-acting Leu-enkephalin analog that is resistant to enzymatic degradation. It can be incorporated in cosmetic formulations such as emulsions, gels, and waxes where removal of the deep lines or wrinkles in the forehead or around the eyes is desired.

TYR-D-ALA-GLY-PHE-LEU/ Pentapeptide-18/ Leuphasyl Chemical Properties
Melting point 160-163.5 °C
Boiling point 991.9±65.0 °C(Predicted)
density 1.257±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka 3.40±0.10(Predicted)
InChIKey ZHUJMSMQIPIPTF-JMBSJVKXSA-N

Pentapeptide 18/Leuphasyl Benefits
Pentapeptide-18 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. It targets in vitro the wrinkle-formation mechanism of expression wrinkles in a new way, offering an alternative to peptides like Acetyl Hexapeptide-3. It can be incorporated in cosmetic formulations such as emulsions, gels, and waxes.

Pentapeptide-18 is a neuropeptide mimicing the natural mechanism of enkephalins, that gives botulinum like results. It reduces the depth of stretch marks and wrinkles caused by the muscle contractions.

Pentapeptide-18 has been used in anti-wrinkle eye serum to reduce the the appearance of fine lines and wrinkles-crow’s feet with significant improvement in skin roughness. It may work synergistically with Argirilene and increase the benefits notablely.
Functions and Applications of Pentapeptide 18/Leuphasyl
1.Improve microcirculation of the blood.
2.Strengthen blood circulation.
3.Eliminate inflammation.
4.Resist pouch and dilute the fine lines and cow’s feet around eyes.
5.Delay the effects of premature aging by improving the elasticity and firmness of the skin.