Melanotan 1/ Melanotan I/ Afamelanotide CAS 75921-69-6

Melanotan 1/ Melanotan I/ Afamelanotide CAS 75921-69-6

Product Name: Melanotan 1
Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Synonyms: [NLE4,D-PHE]ALPHA-MELANOCYTE STIMULATING HORMONE;(NLE4,D-PHE7)-ALPHA-MSH;[Nle4,D-Phe7]α-MSH;Ac-L-Ser-L-Tyr-L-Ser-L-Nle-L-Glu-L-His-D-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2;N-Ac-L-Ser-L-Tyr-L-Ser-L-Nle-L-Glu-L-His-D-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-NH2;[Nle4,DPhe7] a-MSH, amide;[Nle4,DPhe7] a-MSH, amide:Melanotan Ⅰ;[Nle4, D-Phe7]-α-MSH, amide
CAS: 75921-69-6
MF: C78H111N21O19
MW: 1646.85
EINECS: 211-519-9
Product Categories: Ion Channel Modulating Peptides;Melanocyte Stimulating Hormones (MSH);ImmunomodulatorsHormones;Obesity Research;Peptides for Cell Biology;Pituitary Hormones;Peptide;Melanocyte Stimulating Hormone (MSH)Peptides and Proteins;α-Melanocyte Stimulating Hormone (α-MSH)Peptides for Cell Biology;Cytokines Growth Factors and Hormones (Obesity);Melanotan II A
Mol File: 75921-69-6.mol

Melanotan 2 (also known as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in
our body that stimulates melanogenesis, which is responsible for pigmentation of the skin. This peptide hormone, called
alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects.
Indeed, MSH also brings out potent benefits of lipid metabolism, appetite, and sexual libido via these melanocortin receptors.
Hence, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition
to promoting skin tanning. Melanotan 2 has been researched extensively to use in protecting against the harmful effects of ultraviolet
radiation from sunlight because of its melanogenesis-stimulating features.
Additionally, Melanotan 2(MT-2) and a similar synthetically produced variant, , have been studied as a potential remedy
for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

Melanotan 1/ Melanotan I/ Afamelanotide CAS 75921-69-6 Chemical Properties
density 1.46±0.1 g/cm3(Predicted)
RTECS OS1830200
storage temp. −20°C
pka 4.43±0.10(Predicted)
InChIKey UAHFGYDRQSXQEB-LEBBXHLNSA-N
CAS DataBase Reference 75921-69-6(CAS DataBase Reference)

Uses of Melanotan 1/ Melanotan I/ Afamelanotide CAS 75921-69-6s
With the release of Melanotan I, this linear peptide consisting of 13 amino acids is bound to play an even greater role in drug research. The main English names of Melanotan I are Melanotan-1 and Afamelanotide, which belong to α-MSH analogs,Melanotan I can be used to treat photosensitivity disorders caused by erythropoietic protoporphyria.