Hot Sale Vasopressin CAS 11000-17-2 For Lab Research

Hot Sale Vasopressin CAS 11000-17-2 For Lab Research

Product Name: Vasopressin
Synonyms: adh(hormone);leiormone;pitressin;pituitrin;tonephin;vasophysin;1-[19-amino-13-butan-2-yl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[1-(carbamoylmethylcarbamoyl)-4-(diaminomethylideneamino)butyl]pyrrolidine-2-carboxamide;VASOPRESSIN ACETATE
CAS: 11000-17-2
MF: C46H65N13O12S2
MW: 1056.22
EINECS: 234-236-2
Product Categories:
Mol File: 11000-17-2.mol

Antidiuretic hormone, also known as vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. Antidiuretic hormone binds to receptors in the distal or collecting tubules of the kidney and promotes reabsorbtion of water back into the circulation.

Vasopressin CAS 11000-17-2 Chemical Properties
form Lyophilized Powder
color White
Water Solubility Soluble in water (Miscible).
CAS DataBase Reference 11000-17-2(CAS DataBase Reference)

Function and Application of Vasopressin CAS 11000-17-2
Vasopressin acts on three different receptors, vasopressin receptor V1a (which initiates vasoconstriction, liver gluconeogenesis, platelet aggregation and release of factor VIII), vasopressin receptor V1b (which mediates corticotrophin secretion from the pituitary) and vasopressin receptor V2 which controls free water reabsorption in the renal medullar. The binding of vasopressin to the V2 receptor activates adenylate cyclase which causes the release of aquaporin 2 channels into the cells lining the renal medullar duct. This allows water to be reabsorbed down an osmotic gradient so the urine is more concentrated.

In human medicine, vasopressin has been used to treat acute GI hemorrhage and to stimulate GI peristalsis. Vasopressin CRI is also being used for treatment of hypotensive septic patients unresponsive to conventional vasopressor. Prior to radiographic procedures, it has been used to dispel interfering gas shadows or help concentrate contrast media.