Hot Sale Plecanatide CAS 467426-54-6 Use For Treat chronic idiopathic constipation (CIC)

Hot Sale Plecanatide CAS 467426-54-6 Use For Treat chronic idiopathic constipation (CIC)

Product Name: Plecanatide
Synonyms: Plecanatide;ASN-ASP-GLU-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BOND CYS1&CYS3,CYS2&CYS4);Plecanatide Impurtiy;L-Leucine, L-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12),(7→15)-bis(disulfide);Plecanatide fandachem;Plecanatide impurity;Plecanatide USP/EP/BP;Prikanatide
CAS: 467426-54-6
MF: C65H104N18O26S4
MW: 1681.89
Mol File: 467426-54-6.mol

Plecanatide is a new drug that affects the enzyme guanylate cyclase, stimulating intestinal fluid secretion and accelerating bowel movements. The oral peptide, composed of 16 amino acids, is designed to mimic urinary guanosine, a human gastrointestinal peptide. Originally developed by Callisto Pharmaceuticals in the United States and transferred to Synergy Pharmaceuticals for development, procainatide was approved for marketing by the U.S. Food and Drug Administration (FDA) on January 19Chemicalbook 2017 for the treatment of CIC in adults.Procainatide is an analogue of uroguanosine (uroguanylin) and contains a 16 It is an analog of uroguanylin, a cyclic peptide containing 16 amino acids, and has the function of a guanylate cyclase receptor agonist that promotes urinary sodium excretion, regulates acid-base ions in the gastrointestinal tract, induces fluid transport into the gastrointestinal tract, and increases peristalsis of the gastrointestinal tract.

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Function and Application of Plecanatide
Procainide is a guanylatecyclase-C (GC-C) receptor agonist that promotes urinary sodium excretion, regulates acid-base ions in the gastrointestinal tract, induces fluid transport into the gastrointestinal tract, and increases peristalsis in the gastrointestinal tract, and is indicated for the treatment of CIC in adults.