Glutathione Powder CAS 70-18-8 for Nutrient Supplements Skin Whitening Reduced Glutathione Powder L-Glutathione
Product Name: Glutathione
Synonyms: glutatiol;glutatione;glutide;glutinal;isethion;l-glutatione;N(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine;n-(n-l-gamma-glutamyl-l-cysteinyl)-glycin
CAS: 70-18-8
MF: C10H17N3O6S
MW: 307.32
EINECS: 200-725-4
Product Categories: chemical;Inhibitors;Amino Acids & Derivatives;Material;Pharmaceutical intermediates;pharmaceutical;pharmacetical;Amino Acids 13C, 2H, 15N;Antioxidant;Biochemistry;Intermediates & Fine Chemicals;Pharmaceuticals;API
Mol File: 70-18-8.mol
Glutathione (GSH), also named Reduced Glutathione, is a tripeptide composed of glutamate, cysteine, and glycine. It can be found in almost every cell of human body. Nowadays, the industrial production of Glutathione is mainly obtained by enzymatic synthesis. In the method, Glutathione has a high purity and good water-solubility. As an active tripeptide with important physiological functions, Glutathione is the most important non-protein sulfhydryl compound in organisms. It has biological activities such as detoxification, anti-oxidation, free radical scavenging, skin whitening and spot-fading. Therefore, it is widely used in cosmetics, medicine, health care products and other industries. It can be soluble in water greatly and easy to be added into all kinds of skin-whitening cosmetics. Plamed Glutathione is divided into cosmetics grade and medical grade.
Glutathione CAS 70-18-8 Chemical Properties
Melting point 192-195 °C (dec.) (lit.)
alpha -16.5 º (c=2, H2O)
Boiling point 754.5±60.0 °C(Predicted)
density 1.4482 (rough estimate)
refractive index -17 ° (C=2, H2O)
storage temp. 2-8°C
solubility H2O: 50 mg/mL
pka pK1 2.12; pK2 3.53; pK3 8.66; pK4 9.12(at 25℃)
form powder
color White
Odor Odorless
PH 3 (10g/l, H2O, 20°C)
Water Solubility soluble
Merck 14,4475
BRN 1729812
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey RWSXRVCMGQZWBV-WDSKDSINSA-N
CAS DataBase Reference 70-18-8(CAS DataBase Reference)
EPA Substance Registry System Glutathione (70-18-8)
Glutathione Manufacturer Process Flow Chart
Glutathione CAS 70-18-8 Benefits
1.Whiten skin and remove freckle
Glutathione can chelate internal and external toxins such as heavy metals. It can prevent skin pigmentation. Also it can inhibit the formation of new melanin and reduce its oxidation. Glutathione alleviates skin problems such as chloasma. It has a great function of lightening skin and removing freckles. Meanwhile, Glutathione is small molecular peptide. So it can easily penetrate cell membrane and be absorbed by the skin, when applied externally. It is an effective cosmetic ingredient for whitening skin
2.Anti-oxidation
Glutathione’s structure contains a lively thiol group-SH. So it is easily oxidized and dehydrogenated. The free radicals can be reduced directly into acidic substances by combining the thiol group with free radicals in the body. Thereby it accelerates the elimination of the free radicals; and fight against free radical damage to the skin. At the same time, Glutathione is a kind of radiation protective agent. It can enable radiation to produce highly active free radicals in living organisms through direct and indirect action. And then Glutathione can clear away these free radicals to achieve its anti-oxidant effect.
3.Isolate PM2.5
Glutathione can isolate the damage of PM2.5 to the skin, when acting on the skin surface.
Glutathione CAS 70-18-8 Application and Reference Dosage
Glutathione is mainly used in whitening skin care products, such as serum, facial mask, emulsion, toner, essence, cream, etc.
Product | Reference Dosage |
Glutathione 98% | 0.1-0.5% |
Attention of Glutathione CAS 70-18-8:
Glutathione cannot be used with vitamin B12, orotic acid (vitamin B13) into cosmetics, or it will cause skin irritation
Application of Glutathione CAS 70-18-8
GSH is the primary active state, accounting for about 95%; GSSG is about 1% inactive;
GSH has only peptide bonds, and GSSG also contains a disulfide bond;
GSH binding ability is stronger than GSSG;
Glutathione reductase catalyzes the interconversion between GSH and GSSG.
Believe you should have a preliminary understanding of glutathione. Let’s go further.
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