Cardiovascular system peptide

Cardiovascular system peptide including Carperitide Acetate/ ANP 1-28, HUMAN CAS 89213-87-6 For Treatment Of Congestive Heart Failure, Nesiritide / BNP-32 (HUMAN) CAS 124584-08-3 Brain Natriuretic Peptide For Heart Failure.

Carperitide CAS 89213-87-6 is the α-human atrial natriuretic peptide (α-hANP) produced by recombinant technology. It was introduced in Japan as a treatment for acute congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the elevated left ventricular end-diastolic pressure and the index of myocardial oxygen consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was effective in improving hemodynamics and symptoms in 60% of patients with acute CHF. Carperitide was reported to be well tolerated with no significant adverse effects clinically. A beneficial effect on hemodynamics has been reported in chronic heart failure patients. Carperitide is also in clinical trials for maintenance of blood pressure during surgical operations.

Function and Application of Nesiritide / BNP-32 (HUMAN) CAS 124584-08-3
Treatment of congestive heart failure (renin-angiotensin system antagonist).