Hexapeptide-10/ Serilesine CAS 146439-94-3 Widely used in moisturizers, creams, facial masks, eye creams

Hexapeptide-10/ Serilesine CAS 146439-94-3 Widely used in moisturizers, creams, facial masks, eye creams

Product Name: Hexapeptide-10
Product description: Stimulate skin tissue repair, reshape the biochemical function of skin, thus improve skin firmness, used for anti-wrinkle and anti-aging.
CAS: 146439-94-3
Sequence: H-Ser-Ile-Lys-Val-Ala-Val-OH
Molecular formula: C28H53N7O8
Molecular weight: 615.76252

Hexapeptide-10 is from an adhesion sequence of laminin, which restores the cutaneous structure.Hexapeptide-10 is a firming active that promotes a double-cellular activity on both keratinocytes and fibroblast. It increases the synthesis of laminin-5, alpha6-integrin and hemidesmosomes, thus strengthening the dermal-epidermal junction. With Hexapeptide-10,the skin is restructured, replenished, firmer and more elastic, recovering its fullness.

Function of Hexapeptide-10/ Serilesine CAS 146439-94-3
The Hexapeptide-10 corresponds to residues 2099-2104 of the laminin α1 chain. Hexapeptide-10 has been
shown to modulate tumor invasion, metastasis and angiogenesis. It also induced the synthesis of
prostaglandin E2, interstitial collagenase, and gelatinase B in monocyte cell cultures. Laminin fragments
containing the SIKVAV sequence may contribute to the inflammatory response at sites of wound healing.
They may also play a role in the excessive induction of metalloproteinases in chronic inflammatory lesions.

Application of Hexapeptide-10/ Serilesine CAS 146439-94-3
Hexapeptide-10 is from an adhesion sequence of laminin, which restores the cutaneous structure.
Hexapeptide-10 is a firming active that promotes a double-cellular activity on both keratinocytes and
fibroblast. It increases the synthesis of laminin-5, alpha6-integrin and hemidesmosomes, thus
strengthening the dermal-epidermal junction. With Hexapeptide-10,the skin is restructured, replenished,
firmer and more elastic, recovering its fullness.

Uses of Hexapeptide-10/ Serilesine CAS 146439-94-3
1. Widely used in moisturizers, creams, facial masks, eye creams and bath products.
2. Used in conjunction with high-sweetness sweeteners such as NHDC, it can make the sweet taste softer and achieve the effect of improving the flavor of food.